Hydrocortisone Cream Market Report: Sales Volume, Market Share, Leading Brands & Market Trends

Benadryl is the best-performing hydrocortisone cream brand in July 2026, moving 90,000 units across 2 ASINs for 37.7% of Top 10 volume. Cortizone 10 follows with 70,000 units (29.3%), ahead of Amazon Basic Care on 30,000 units (12.6%).

With 7 brands splitting the Top 10 and 79.5% of volume sitting with three of them, this is a concentrated shelf — the leaders hold multiple listings or one very high-velocity ASIN, so a new entrant competes against established review moats rather than an open field. Average selling prices among the leaders run from $5.58 to $8.47, which frames the price band a competing listing has to justify.

Based on July 2026 data, this shortlist surfaces the two kinds of ASIN worth keeping an eye on — the ones that just broke into the Top 10, and the ones growing fastest month over month. On the growth side, B0779CBH6S leads positive momentum with ▲ 200.0% MoM growth on 30K units, with B0006GDBB8 close behind at ▲ 100.0% MoM on 200 units.

The two signals carry different weight. A fresh entrant means share has already changed hands — an incumbent gave up its place to make room, so any competitive set drawn up a month ago is now out of date. A steep growth rate works as the earlier warning: it marks demand that is still compounding, usually a month or two before the ranking catches up to it.