Benadryl Market Report: Sales Volume, Market Share, Leading Brands & Market Trends
Benadryl sales on Amazon US totaled 138,900 units in July 2026 (▼ 17.7% vs. the prior month), generating an estimated $983,785 in revenue across the 50 top-ranked ASINs for this search term. Demand is heavily concentrated at the top of the ranking — the ten best performers capture 99.8% of unit volume and 99.6% of revenue, while a typical listing is priced at $14.20. The keyword itself pulled 420,368 Amazon queries over the same period (▲ 11.2% MoM).
Zooming out to the 12-month window ending July 2026, the benadryl Top 50 moved 927,400 units and $6,403,775 in cumulative sales — an average of 77,283 units and $533,648 per month. Monthly throughput topped out at 168,850 units in June 2026 and dipped to 34,150 in February 2026, leaving the latest reading 16.7% higher than August 2025.
Benadryl Sales Trend (Trailing 12 Months)
Based on the top 50 ASINs by monthly sales for this keyword
2025/08
2025/09
2025/10
2025/11
2025/12
2026/01
2026/02
2026/03
2026/04
2026/05
2026/06
2026/07
Monthly Sales 2026/07
138.9K
▼ 17.7% MoM
Monthly Revenue 2026/07
$983.8K
▼ 11.7% MoM
Top 10 Market Share 2026/07
99.8%
Benadryl Market Share & Sales Concentration on Amazon US — July 2026
The most-sold benadryl listing on Amazon US in July 2026 is ASIN B00HQRCNWI (Brand: Benadryl), which sold 80,000 units at $6.48 apiece — equal to 57.6% of every unit tracked in this report and 4.0× the volume of the No. 2 listing.
The Top 10 ASINs account for 138,600 units and $979,560 in July 2026 — 99.8% of unit volume and 99.6% of revenue among all 50 ranked ASINs in this report.
Sales Volume of Top ASINs for 'Benadryl' on Amazon
July 2026









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Top 5 Volume Share breakdown

B00HQRCNWI
Benadryl Itch Relief Gel Extra Strength, 2% Diphenhydramine HCl, 3.5 fl. Oz
80K
▼ 20.0%vs. prior month
$518.4K
latest month
12-month trend

B012SAJYEM
Benadryl Itch Relief Stick, Extra Strength, 0.47 fl. Oz | For Rashes, Insect and Bug Bites, Fits in Backpack or First Aid Kit, Outdoor Activities, Sporting Events, Picnics, Camping
20K
▼ 33.3%vs. prior month
$58.2K
latest month
12-month trend

B01J24FQPS
Benadryl Extra Strength Itch Stopping Cream, Diphenhydramine HCl, 1 oz
10K
▲ 0.0%vs. prior month
$54.8K
latest month
12-month trend

B00HANX066
Benadryl Extra Strength Itch Cooling Spray, Topical Analgesic 2 fl. oz | Diphenhydramine HCl & Zinc Acetate Skin Protectant, Fast Relief from Insect Bites, Travel Size
10K
▲ 0.0%vs. prior month
$55.9K
latest month
12-month trend

B07PJ5TNPP
After Bite Advanced Bug Bite Itch Relief, Portable Pen Applicator, 4Pk | 5% Sodium Bicarbonate Liquid in a Travel-Size Applicator Pen Relieves Itch from Bug Bites, Bees & Poison Ivy
10K
▲ 0.0%vs. prior month
$212.9K
latest month
12-month trend

B0CM7Z667L
Bactine MAX Antibiotic + Pain Relieving Ointment - Antibiotic Ointment with Lidocaine - Pain + Itch Relief for Minor Cuts & Scrapes & Burns - Lidocaine Numbing Cream - 0.5oz | Antibiotic Ointment with Lidocaine, Pain and Itch Relief for Minor Cuts, Scrapes, and Burns, Lidocaine Numbing Cream
4K
▼ 20.0%vs. prior month
$19.9K
latest month
12-month trend
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Best Benadryl Brands on Amazon US — Top 3 Brand Sales Concentration (July 2026)
Benadryl is the best-performing benadryl brand in July 2026, moving 124,600 units across 8 ASINs for 89.9% of Top 10 volume. After Bite follows with 10,000 units (7.2%), ahead of Bactine on 4,000 units (2.9%).
With 3 brands splitting the Top 10 and 100.0% of volume sitting with three of them, this is a concentrated shelf — the leaders hold multiple listings or one very high-velocity ASIN, so a new entrant competes against established review moats rather than an open field. Average selling prices among the leaders run from $4.97 to $21.29, which frames the price band a competing listing has to justify.
Brand share of Top 10 volume
Benadryl
8 ASINs in Top 10
89.9%
Units
124.6K
Revenue
$746.8K
Avg. price
$11.93

B00HQRCNWI
$6.48·★4.6·45.4K revsBenadryl Itch Relief Gel Extra Strength, 2% Diphenhydramine HCl, 3.5 fl. Oz
Units sold80K
B012SAJYEM
$2.89·★4.5·3.6K revsBenadryl Itch Relief Stick, Extra Strength, 0.47 fl. Oz | For Rashes, Insect and Bug Bites, Fits in Backpack or First Aid Kit, Outdoor Activities, Sporting Events, Picnics, Camping
Units sold20K
B01J24FQPS
$5.48·★4.7·4.5K revsBenadryl Extra Strength Itch Stopping Cream, Diphenhydramine HCl, 1 oz
Units sold10K
B00HANX066
$5.49·★4.7·3.6K revsBenadryl Extra Strength Itch Cooling Spray, Topical Analgesic 2 fl. oz | Diphenhydramine HCl & Zinc Acetate Skin Protectant, Fast Relief from Insect Bites, Travel Size
Units sold10K
B00169T23U
$6.79·★4.7·7.8K revsBenadryl Original Strength Anti-Itch Cream, Diphenhydramine HCl, 1 oz
Units sold2K
B09B6KS9YM
$15.43·★4.7·2.7K revsBenadryl Extra Strength Anti-Itch Cream, 2% Diphenhydramine HCl, 3 x 1 oz | Topical Cream for Itch Relief of Outdoor Itches, Poison Ivy, Insect Bites & More
Units sold2K
B07VLNHG8H
$18.99·★4.7·2.9K revsBenadryl Cooling Anti-Itch Spray 2 fl. Oz and Benadryl Extra Strength Itch Relief Stick 0.47 fl. oz, Both with Diphenhydramine 1 ea
Units sold500
B001ECQ7M8
$33.93·★4.7·87 revsBenadryl Itch Stopping Spray, Extra Strength, 2 Ounce (Pack of 4)
Units sold100
After Bite
1 ASIN in Top 10
7.2%
Units
10K
Revenue
$212.9K
Avg. price
$21.29

B07PJ5TNPP
$21.29·★4.6·6.2K revsAfter Bite Advanced Bug Bite Itch Relief, Portable Pen Applicator, 4Pk | 5% Sodium Bicarbonate Liquid in a Travel-Size Applicator Pen Relieves Itch from Bug Bites, Bees & Poison Ivy
Units sold10K
Bactine
1 ASIN in Top 10
2.9%
Units
4K
Revenue
$19.9K
Avg. price
$4.97

B0CM7Z667L
$4.97·★4.7·1.5K revsBactine MAX Antibiotic + Pain Relieving Ointment - Antibiotic Ointment with Lidocaine - Pain + Itch Relief for Minor Cuts & Scrapes & Burns - Lidocaine Numbing Cream - 0.5oz | Antibiotic Ointment with Lidocaine, Pain and Itch Relief for Minor Cuts, Scrapes, and Burns, Lidocaine Numbing Cream
Units sold4K
Trending Benadryl Products — Growth Leaders & New Top 10 Entrants
Based on July 2026 data, this shortlist surfaces the two kinds of ASIN worth keeping an eye on — the ones that just broke into the Top 10, and the ones growing fastest month over month. Specifically, one ASIN forced its way in: B001ECQ7M8 booked 100 units at $33.93, with ▲ 100.0% MoM change. On the growth side, B09B6KS9YM leads positive momentum with ▲ 100.0% MoM growth on 2K units.
The two signals carry different weight. A fresh entrant means share has already changed hands — an incumbent gave up its place to make room, so any competitive set drawn up a month ago is now out of date. A steep growth rate works as the earlier warning: it marks demand that is still compounding, usually a month or two before the ranking catches up to it.

B001ECQ7M8
Benadryl Itch Stopping Spray, Extra Strength, 2 Ounce (Pack of 4)
Price
$33.93
Rating
4.7
Reviews
87
Latest month sales

B09B6KS9YM
Benadryl Extra Strength Anti-Itch Cream, 2% Diphenhydramine HCl, 3 x 1 oz | Topical Cream for Itch Relief of Outdoor Itches, Poison Ivy, Insect Bites & More
Price
$15.43
Rating
4.7
Reviews
2.7K
Latest month sales
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