Enzymatic Cleaner Market Report: Sales Volume, Market Share, Leading Brands & Market Trends

July 2026

Enzymatic Cleaner sales on Amazon US totaled 500,000 units in July 2026 (▲ 8.3% vs. the prior month), generating an estimated $10,413,760 in revenue across the 50 top-ranked ASINs for this search term. Demand is heavily concentrated at the top of the ranking — the ten best performers capture 56.0% of unit volume and 48.7% of revenue, while a typical listing is priced at $22.55. The keyword itself pulled 21,995 Amazon queries over the same period (▼ 3.6% MoM).

Zooming out to the 12-month window ending July 2026, the enzymatic cleaner Top 50 moved 4,295,100 units and $91,108,681 in cumulative sales — an average of 357,925 units and $7,592,390 per month. Monthly throughput topped out at 500,000 units in July 2026 and dipped to 244,700 in May 2026, leaving the latest reading 56.5% higher than August 2025.

4.3MTotal units sold · Last 12 months
$91.1MTotal revenue · Last 12 months
22K▼ 3.6% MoM
Monthly search volume
$22.55Avg. price · July 2026

Enzymatic Cleaner Sales Trend (Trailing 12 Months)

Based on the top 50 ASINs by monthly sales for this keyword

Sales
Revenue

2025/08

Sales319.5K
Revenue$6.9M

2025/09

Sales324.6K
Revenue$7.2M

2025/10

Sales339.8K
Revenue$7.2M

2025/11

Sales359.1K
Revenue$7.6M

2025/12

Sales262.9K
Revenue$5.8M

2026/01

Sales293.1K
Revenue$6.2M

2026/02

Sales369.7K
Revenue$7.6M

2026/03

Sales401.9K
Revenue$8.4M

2026/04

Sales418K
Revenue$8.9M

2026/05

Sales244.7K
Revenue$5.1M

2026/06

Sales461.8K
Revenue$9.8M
500K

2026/07

Sales500K
Revenue$10.4M
25/0925/1126/0126/0326/0526/07
ASINSIGHT
Source: www.asinsight.com

Monthly Sales 2026/07

500K

▲ 8.3% MoM

Monthly Revenue 2026/07

$10.4M

▲ 6.4% MoM

Top 10 Market Share 2026/07

56.0%

See the Top 10 ASINs driving 56.0% of sales

Enzymatic Cleaner Market Share & Sales Concentration on Amazon US — July 2026

The most-sold enzymatic cleaner listing on Amazon US in July 2026 is ASIN B00CKFL93K (Brand: Rocco & Roxie Supply Co.), which sold 60,000 units at $18.75 apiece — equal to 12.0% of every unit tracked in this report and 20% ahead of the No. 2 listing.

The Top 10 ASINs account for 280,000 units and $5,070,000 in July 2026 — 56.0% of unit volume and 48.7% of revenue among all 50 ranked ASINs in this report.

Sales Volume of Top ASINs for 'Enzymatic Cleaner' on Amazon

July 2026
ASINSIGHT Logo
56.0% Volume Share 280K units sold
48.7% Revenue Share $5.1M estimated
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Top 5 Volume Share breakdown

B00CKFL93K 12.0%
B0CJH9DRM6 10.0%
B0FK7K482H 6.0%
B09KQTY9YR 4.0%
B002J824AA 4.0%
Others 64.0%
#1
Rocco & Roxie Enzyme Stain & Odor Eliminator, 32 Fl Oz | Bio-enzymatic urine destroyer; CRI Certified Safe; made in USA; for carpets, bedding, litter boxes, crates & cars

B00CKFL93K

Rocco & Roxie Enzyme Stain & Odor Eliminator, 32 Fl Oz | Bio-enzymatic urine destroyer; CRI Certified Safe; made in USA; for carpets, bedding, litter boxes, crates & cars

$18.75· 4.4·127.5K reviews
Monthly Sales

60K

▲ 20.0%

vs. prior month

Revenue

$1.4M

latest month

Monthly Trend

12-month trend

#2
Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood - 64 Loads

B0CJH9DRM6

Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood - 64 Loads

$19.95· 4.6·7.5K reviews
Monthly Sales

50K

▲ 0.0%

vs. prior month

Revenue

$942K

latest month

Monthly Trend

12-month trend

#3
ACTIVE Washing Machine Cleaner for Pet Owners Enzymatic Deep Clean Descaler for Cat & Dog Hair, Urine, Odor, Residue, 24 Septic-Safe Tablets for Top Load, Front Loader, HE Washer Tub - 1 Year Supply

B0FK7K482H

ACTIVE Washing Machine Cleaner for Pet Owners Enzymatic Deep Clean Descaler for Cat & Dog Hair, Urine, Odor, Residue, 24 Septic-Safe Tablets for Top Load, Front Loader, HE Washer Tub - 1 Year Supply

$25.95· 4.6·3.7K reviews
Monthly Sales

30K

▲ 0.0%

vs. prior month

Revenue

$749.4K

latest month

Monthly Trend

12-month trend

#4
Nature's Miracle Cat Urine Destroyer Plus, Enzymatic Cleaner, 32 oz | Destroys the Toughest Cat Urine Stains, For Use on Multiple Surfaces, Safe For Pets and Home*, Fresh Scent

B09KQTY9YR

Nature's Miracle Cat Urine Destroyer Plus, Enzymatic Cleaner, 32 oz | Destroys the Toughest Cat Urine Stains, For Use on Multiple Surfaces, Safe For Pets and Home*, Fresh Scent

$12.72· 4.5·7.1K reviews
Monthly Sales

20K

▲ 0.0%

vs. prior month

Revenue

$254.4K

latest month

Monthly Trend

12-month trend

#5
Chemical Guys, Lightning Fast Carpet & Upholstery Stain Extractor, 16 oz | Tackles coffee, soda, wine and pet messes on carpet, seats and mats, just spray, agitate and blot for a clean look

B002J824AA

Chemical Guys, Lightning Fast Carpet & Upholstery Stain Extractor, 16 oz | Tackles coffee, soda, wine and pet messes on carpet, seats and mats, just spray, agitate and blot for a clean look

$11.97· 4.5·26.5K reviews
Monthly Sales

20K

▲ 100.0%

vs. prior month

Revenue

$239.4K

latest month

Monthly Trend

12-month trend

#6
Nature’s Miracle Advanced Dog Stain & Odor Eliminator, Severe Mess, 32 oz | Enzymatic Cleaner Eliminates the Toughest Dog Messes, For Use on Multiple Surfaces, Safe For Pets and Home*, Fresh Scent

B0723HRWJW

Nature’s Miracle Advanced Dog Stain & Odor Eliminator, Severe Mess, 32 oz | Enzymatic Cleaner Eliminates the Toughest Dog Messes, For Use on Multiple Surfaces, Safe For Pets and Home*, Fresh Scent

$13.57· 4.6·27.7K reviews
Monthly Sales

20K

▲ 0.0%

vs. prior month

Revenue

$271.4K

latest month

Monthly Trend

12-month trend

Unlock to view all Top 50 ASIN competitors and their sales contributions

Best Enzymatic Cleaner Brands on Amazon US — Top 3 Brand Sales Concentration (July 2026)

ACTIVE is the best-performing enzymatic cleaner brand in July 2026, moving 80,000 units across 2 ASINs for 28.6% of Top 10 volume. Nature's Miracle follows with 80,000 units (28.6%), ahead of Rocco & Roxie Supply Co. on 60,000 units (21.4%).

With 6 brands splitting the Top 10 and 78.6% of volume sitting with three of them, this is a concentrated shelf — the leaders hold multiple listings or one very high-velocity ASIN, so a new entrant competes against established review moats rather than an open field. Average selling prices among the leaders run from $12.45 to $22.95, which frames the price band a competing listing has to justify.

Brand share of Top 10 volume

28.6%
28.6%
21.4%
21.4%
ACTIVE
Nature's Miracle
Rocco & Roxie Supply Co.
Other brands
1

ACTIVE

2 ASINs in Top 10

28.6%

Units

80K

Revenue

$1.7M

Avg. price

$22.95

  • Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood - 64 Loads

    B0CJH9DRM6

    $19.95·4.6·7.5K revs

    Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood - 64 Loads

    Units sold50K
  • ACTIVE Washing Machine Cleaner for Pet Owners Enzymatic Deep Clean Descaler for Cat & Dog Hair, Urine, Odor, Residue, 24 Septic-Safe Tablets for Top Load, Front Loader, HE Washer Tub - 1 Year Supply

    B0FK7K482H

    $25.95·4.6·3.7K revs

    ACTIVE Washing Machine Cleaner for Pet Owners Enzymatic Deep Clean Descaler for Cat & Dog Hair, Urine, Odor, Residue, 24 Septic-Safe Tablets for Top Load, Front Loader, HE Washer Tub - 1 Year Supply

    Units sold30K
2

Nature's Miracle

4 ASINs in Top 10

28.6%

Units

80K

Revenue

$991.2K

Avg. price

$12.45

  • Nature's Miracle Cat Urine Destroyer Plus, Enzymatic Cleaner, 32 oz | Destroys the Toughest Cat Urine Stains, For Use on Multiple Surfaces, Safe For Pets and Home*, Fresh Scent

    B09KQTY9YR

    $12.72·4.5·7.1K revs

    Nature's Miracle Cat Urine Destroyer Plus, Enzymatic Cleaner, 32 oz | Destroys the Toughest Cat Urine Stains, For Use on Multiple Surfaces, Safe For Pets and Home*, Fresh Scent

    Units sold20K
  • Nature’s Miracle Advanced Dog Stain & Odor Eliminator, Severe Mess, 32 oz | Enzymatic Cleaner Eliminates the Toughest Dog Messes, For Use on Multiple Surfaces, Safe For Pets and Home*, Fresh Scent

    B0723HRWJW

    $13.57·4.6·27.7K revs

    Nature’s Miracle Advanced Dog Stain & Odor Eliminator, Severe Mess, 32 oz | Enzymatic Cleaner Eliminates the Toughest Dog Messes, For Use on Multiple Surfaces, Safe For Pets and Home*, Fresh Scent

    Units sold20K
  • Nature's Miracle Dog Urine Destroyer Plus, Enzymatic Cleaner, 32 oz | Destroys the Toughest Dog Urine Stains, For Use on Multiple Surfaces, Safe For Pets and Home*, Fresh Scent

    B09KQVCC67

    $12.72·4.5·4.6K revs

    Nature's Miracle Dog Urine Destroyer Plus, Enzymatic Cleaner, 32 oz | Destroys the Toughest Dog Urine Stains, For Use on Multiple Surfaces, Safe For Pets and Home*, Fresh Scent

    Units sold20K
  • Nature’s Miracle Dog Stain & Odor Remover, Enzymatic Cleaner, 32 oz | Tough on Dog Urine, Feces, Vomit, Drool and Other Organic Stains and Odors, For Multiple Surfaces, Fresh Scent

    B071W6CQ7S

    $10.77·4.6·23.6K revs

    Nature’s Miracle Dog Stain & Odor Remover, Enzymatic Cleaner, 32 oz | Tough on Dog Urine, Feces, Vomit, Drool and Other Organic Stains and Odors, For Multiple Surfaces, Fresh Scent

    Units sold20K
3

Rocco & Roxie Supply Co.

1 ASIN in Top 10

21.4%

Units

60K

Revenue

$1.4M

Avg. price

$18.75

  • Rocco & Roxie Enzyme Stain & Odor Eliminator, 32 Fl Oz | Bio-enzymatic urine destroyer; CRI Certified Safe; made in USA; for carpets, bedding, litter boxes, crates & cars

    B00CKFL93K

    $18.75·4.4·127.5K revs

    Rocco & Roxie Enzyme Stain & Odor Eliminator, 32 Fl Oz | Bio-enzymatic urine destroyer; CRI Certified Safe; made in USA; for carpets, bedding, litter boxes, crates & cars

    Units sold60K

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