Benadryl Cream Market Report: Sales Volume, Market Share, Leading Brands & Market Trends
Benadryl Cream sales on Amazon US totaled 419,900 units in July 2026 (▼ 4.4% vs. the prior month), generating an estimated $3,795,755 in revenue across the 50 top-ranked ASINs for this search term. Demand is heavily concentrated at the top of the ranking — the ten best performers capture 64.3% of unit volume and 43.6% of revenue, while a typical listing is priced at $10.76. The keyword itself pulled 64,081 Amazon queries over the same period (▼ 0.7% MoM).
Zooming out to the 12-month window ending July 2026, the benadryl cream Top 50 moved 3,135,950 units and $30,494,873 in cumulative sales — an average of 261,329 units and $2,541,239 per month. Monthly throughput topped out at 439,450 units in June 2026 and dipped to 161,800 in May 2026, leaving the latest reading 30.9% higher than August 2025.
Benadryl Cream Sales Trend (Trailing 12 Months)
Based on the top 50 ASINs by monthly sales for this keyword
2025/08
2025/09
2025/10
2025/11
2025/12
2026/01
2026/02
2026/03
2026/04
2026/05
2026/06
2026/07
Monthly Sales 2026/07
419.9K
▼ 4.4% MoM
Monthly Revenue 2026/07
$3.8M
▼ 5.3% MoM
Top 10 Market Share 2026/07
64.3%
Benadryl Cream Market Share & Sales Concentration on Amazon US — July 2026
The most-sold benadryl cream listing on Amazon US in July 2026 is ASIN B00HQRCNWI (Brand: Benadryl), which sold 80,000 units at $6.48 apiece — equal to 19.1% of every unit tracked in this report and 2.0× the volume of the No. 2 listing.
The Top 10 ASINs account for 270,000 units and $1,654,800 in July 2026 — 64.3% of unit volume and 43.6% of revenue among all 50 ranked ASINs in this report.
Sales Volume of Top ASINs for 'Benadryl Cream' on Amazon
July 2026









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Top 5 Volume Share breakdown

B00HQRCNWI
Benadryl Itch Relief Gel Extra Strength, 2% Diphenhydramine HCl, 3.5 fl. Oz
80K
▼ 20.0%vs. prior month
$518.4K
latest month
12-month trend

B0BJMQBSKJ
Cortizone-10 Maximum Strength Soothing Aloe Itch Relief Cream, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac & More, 2 oz
40K
▼ 20.0%vs. prior month
$318.8K
latest month
12-month trend

B0779CBH6S
Amazon Basic Care Hydrocortisone 1% Anti-Itch Cream, White, 2 Ounce (Pack of 1)
30K
▲ 200.0%vs. prior month
$162.9K
latest month
12-month trend

B0CMVYX6VN
Cortizone-10 Max Strength Intensive Healing Itch Relief Cream, 2 oz. | 1% hydrocortisone, fast-acting, anti-itch cream for bug bites, rash, eczema, psoriasis, poison ivy, oak, sumac and more
30K
▲ 50.0%vs. prior month
$242.7K
latest month
12-month trend

B012SAJYEM
Benadryl Itch Relief Stick, Extra Strength, 0.47 fl. Oz | For Rashes, Insect and Bug Bites, Fits in Backpack or First Aid Kit, Outdoor Activities, Sporting Events, Picnics, Camping
20K
▼ 33.3%vs. prior month
$58.2K
latest month
12-month trend

B07J3GCHXQ
Amazon Basics Max Strength Anti-Itch Cream, Hydrocortisone 1% Intensive Healing Formula, Itch Relief for Bug Bites, Eczema, Psoriasis, Poison Ivy, Oak and Sumac, 1 ounce (Previously Amazon Basic Care)
20K
▼ 33.3%vs. prior month
$74.6K
latest month
12-month trend
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Best Benadryl Cream Brands on Amazon US — Top 3 Brand Sales Concentration (July 2026)
Benadryl is the best-performing benadryl cream brand in July 2026, moving 120,000 units across 4 ASINs for 44.4% of Top 10 volume. Cortizone 10 follows with 70,000 units (25.9%), ahead of Amazon Basics on 40,000 units (14.8%).
With 5 brands splitting the Top 10 and 85.2% of volume sitting with three of them, this is a concentrated shelf — the leaders hold multiple listings or one very high-velocity ASIN, so a new entrant competes against established review moats rather than an open field. Average selling prices among the leaders run from $3.56 to $8.47, which frames the price band a competing listing has to justify.
Brand share of Top 10 volume
Benadryl
4 ASINs in Top 10
44.4%
Units
120K
Revenue
$687.3K
Avg. price
$5.09

B00HQRCNWI
$6.48·★4.6·45.5K revsBenadryl Itch Relief Gel Extra Strength, 2% Diphenhydramine HCl, 3.5 fl. Oz
Units sold80K
B012SAJYEM
$2.89·★4.5·3.6K revsBenadryl Itch Relief Stick, Extra Strength, 0.47 fl. Oz | For Rashes, Insect and Bug Bites, Fits in Backpack or First Aid Kit, Outdoor Activities, Sporting Events, Picnics, Camping
Units sold20K
B01J24FQPS
$5.48·★4.7·4.5K revsBenadryl Extra Strength Itch Stopping Cream, Diphenhydramine HCl, 1 oz | Zinc Acetate Skin Protectant, Topical Analgesic Cream, Anti-Itch Ointment, Insect Bite & Sunburn Relief
Units sold10K
B00HANX066
$5.49·★4.7·3.6K revsBenadryl Extra Strength Itch Cooling Spray, Topical Analgesic 2 fl. oz | Diphenhydramine HCl & Zinc Acetate Skin Protectant, Fast Relief from Insect Bites, Travel Size
Units sold10K
Cortizone 10
2 ASINs in Top 10
25.9%
Units
70K
Revenue
$561.5K
Avg. price
$8.47

B0BJMQBSKJ
$7.97·★4.7·11.1K revsCortizone-10 Maximum Strength Soothing Aloe Itch Relief Cream, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac & More, 2 oz
Units sold40K
B0CMVYX6VN
$8.97·★4.8·8.5K revsCortizone-10 Max Strength Intensive Healing Itch Relief Cream, 2 oz. | 1% hydrocortisone, fast-acting, anti-itch cream for bug bites, rash, eczema, psoriasis, poison ivy, oak, sumac and more
Units sold30K
Amazon Basics
2 ASINs in Top 10
14.8%
Units
40K
Revenue
$153.2K
Avg. price
$3.56

B07J3GCHXQ
$3.73·★4.6·8.9K revsAmazon Basics Max Strength Anti-Itch Cream, Hydrocortisone 1% Intensive Healing Formula, Itch Relief for Bug Bites, Eczema, Psoriasis, Poison Ivy, Oak and Sumac, 1 ounce (Previously Amazon Basic Care)
Units sold20K
B0BJRS2F8H
$3.39·★4.7·3.5K revsAmazon Basics Medicated Calamine Anti-Itch Lotion, 6 Fluid Ounce, 1-Pack, for Insect Bites, Poison Ivy and Rashes (Previously Solimo) (New Formula)
Units sold20K
Trending Benadryl Cream Products — Growth Leaders & New Top 10 Entrants
Based on July 2026 data, this shortlist surfaces the two kinds of ASIN worth keeping an eye on — the ones that just broke into the Top 10, and the ones growing fastest month over month. Specifically, one ASIN forced its way in: B01EFPKRSA booked 10K units at $8.99, with ▲ 0.0% MoM change. On the growth side, B00KM2P7DQ leads positive momentum with ▲ 7900.0% MoM growth on 4K units, with B00KM2P7K4 close behind at ▲ 800.0% MoM on 900 units.
The two signals carry different weight. A fresh entrant means share has already changed hands — an incumbent gave up its place to make room, so any competitive set drawn up a month ago is now out of date. A steep growth rate works as the earlier warning: it marks demand that is still compounding, usually a month or two before the ranking catches up to it.

B01EFPKRSA
Badger Bug Bite Itch Relief Stick, Organic, Anti-Itch Balm, Soothing, .6 oz | Natural, organic formula for bug bites, rashes & poison ivy; fast relief, pleasant scent, easy application
Price
$8.99
Rating
4.5
Reviews
2.9K
Latest month sales

B00KM2P7DQ
Caladryl Calamine Lotion for Itching, Insect Bites & Poison Ivy, 6 Fl Oz | Itch Relief Lotion with 8% Calamine & 1% Pramoxine, Helps Relieve Pain and Rashes from Poison Ivy, Oak & Sumac
Price
$5.97
Rating
4.6
Reviews
7.5K
Latest month sales

B00KM2P7K4
Caladryl Dry Skin Lotion for Itching, Insect Bites & Poison Ivy, 6 Fl Oz | Itch Relief Lotion with 1% Pramoxine & 0.1% Zinc Acetate, Helps Relieve Pain and Rashes from Poison Ivy, Oak & Sumac
Unlock to view ASIN details and product titles
Price
$6.49
Rating
4.6
Reviews
2.2K
Latest month sales
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