Simparica Trio Market Report: Sales Volume, Market Share, Leading Brands & Market Trends
Simparica Trio sales on Amazon US totaled 321,000 units in July 2026 (▼ 16.8% vs. the prior month), generating an estimated $13,491,820 in revenue across the 50 top-ranked ASINs for this search term. Demand is heavily concentrated at the top of the ranking — the ten best performers capture 40.5% of unit volume and 46.3% of revenue, while a typical listing is priced at $38.70. The keyword itself pulled 8,622 Amazon queries over the same period (▼ 21.4% MoM).
Zooming out to the 12-month window ending July 2026, the simparica trio Top 50 moved 3,356,700 units and $139,257,472 in cumulative sales — an average of 279,725 units and $11,604,789 per month. Monthly throughput topped out at 397,000 units in April 2026 and dipped to 167,700 in January 2026, leaving the latest reading 3.3% higher than August 2025.
Simparica Trio Sales Trend (Trailing 12 Months)
Based on the top 50 ASINs by monthly sales for this keyword
2025/08
2025/09
2025/10
2025/11
2025/12
2026/01
2026/02
2026/03
2026/04
2026/05
2026/06
2026/07
Monthly Sales 2026/07
321K
▼ 16.8% MoM
Monthly Revenue 2026/07
$13.5M
▼ 15.4% MoM
Top 10 Market Share 2026/07
40.5%
Simparica Trio Market Share & Sales Concentration on Amazon US — July 2026
The most-sold simparica trio listing on Amazon US in July 2026 is ASIN B00B8CG602 (Brand: Seresto), which sold 30,000 units at $59.92 apiece — equal to 9.3% of every unit tracked in this report and 1.5× the volume of the No. 2 listing.
The Top 10 ASINs account for 130,000 units and $6,250,800 in July 2026 — 40.5% of unit volume and 46.3% of revenue among all 50 ranked ASINs in this report.
Sales Volume of Top ASINs for 'Simparica Trio' on Amazon
July 2026









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Top 5 Volume Share breakdown

B00B8CG602
Seresto Flea & Tick Collar For Dogs Over 18 lbs., Treatment & Prevention, Vet-Recommend, 8 Month Protection
30K
▼ 25.0%vs. prior month
$1.8M
latest month
12-month trend

B0002J1FOE
Frontline Plus Flea & Tick Spot Treatment for Large Breed Dogs 45-88 lbs. (Purple) Count of 3
20K
▲ 0.0%vs. prior month
$819.6K
latest month
12-month trend

B07PWB9J43
Capstar for Dogs (nitenpyram), Fast-Acting Oral Flea Treatment for Dogs Over 25+ lbs, Vet-Recommended Flea Medication Tablets Start Killing in 30 Minutes, 6 Doses
10K
▲ 0.0%vs. prior month
$429.7K
latest month
12-month trend

B00008DFGY
Frontline Plus Flea & Tick Spot Treatment for Small Breed Dogs 5-22 lbs. (Orange) Count of 3
10K
▼ 50.0%vs. prior month
$406.2K
latest month
12-month trend

B00B8CG58U
Seresto Small Dog Vet-Recommended Flea & Tick Treatment & Prevention Collar for Dogs Under 18 lbs | 8 Months Protection
10K
▼ 50.0%vs. prior month
$596.5K
latest month
12-month trend

B00I0BWNUG
K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs Over 55 lbs. | 2-Mo Supply
10K
▲ 0.0%vs. prior month
$355.8K
latest month
12-month trend
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Best Simparica Trio Brands on Amazon US — Top 3 Brand Sales Concentration (July 2026)
Seresto is the best-performing simparica trio brand in July 2026, moving 50,000 units across 3 ASINs for 38.5% of Top 10 volume. Frontline follows with 30,000 units (23.1%), ahead of PetArmor on 30,000 units (23.1%).
With 5 brands splitting the Top 10 and 84.6% of volume sitting with three of them, this is a concentrated shelf — the leaders hold multiple listings or one very high-velocity ASIN, so a new entrant competes against established review moats rather than an open field. Average selling prices among the leaders run from $24.82 to $75.94, which frames the price band a competing listing has to justify.
Brand share of Top 10 volume
Seresto
3 ASINs in Top 10
38.5%
Units
50K
Revenue
$3.5M
Avg. price
$75.94

B00B8CG602
$59.92·★4.5·114.6K revsSeresto Flea & Tick Collar For Dogs Over 18 lbs., Treatment & Prevention, Vet-Recommend, 8 Month Protection
Units sold30K
B00B8CG58U
$59.97·★4.4·54.8K revsSeresto Small Dog Vet-Recommended Flea & Tick Treatment & Prevention Collar for Dogs Under 18 lbs | 8 Months Protection
Units sold10K
B00WMMMHNM
$107.92·★4.5·114.6K revsSeresto Large Dog Vet-Recommended Flea & Tick Treatment & Prevention Collar for Dogs Over 18 lbs. | 2-Pack
Units sold10K
Frontline
2 ASINs in Top 10
23.1%
Units
30K
Revenue
$1.2M
Avg. price
$40.98

B0002J1FOE
$40.98·★4.4·37.3K revsFrontline Plus Flea & Tick Spot Treatment for Large Breed Dogs 45-88 lbs. (Purple) Count of 3
Units sold20K
B00008DFGY
$40.98·★4.4·49.6K revsFrontline Plus Flea & Tick Spot Treatment for Small Breed Dogs 5-22 lbs. (Orange) Count of 3
Units sold10K
PetArmor
3 ASINs in Top 10
23.1%
Units
30K
Revenue
$746.4K
Avg. price
$24.82

B00WWP1U7I
$25.89·★4.2·62.3K revsPetArmor Plus Flea and Tick Prevention for Dogs, Small Dog Flea and Tick Treatment, 3 Doses, Waterproof Topical, Fast Acting (5-22 lbs)
Units sold10K
B07CXQQ4Q5
$18.84·★4.6·14.2K revsPetArmor 7 Way De-Wormer for Dogs, Oral Treatment for Tapeworm, Roundworm & Hookworm in Large Dogs & Puppies (Over 25 lbs), Worm Remover, Puppy Dewormer (Praziquantel & Pyrantel Pamoate), 2 Chewables
Units sold10K
B07GN2JYSJ
$29.74·★4.4·18.6K revsPetArmor CAPACTION (nitenpyram) Oral Flea Treatment for Cats, Cat Flea Treatment Pill, Fast Acting Tablets Start Killing in 30 Minutes, 2-25 lbs, 6 Doses
Units sold10K
Trending Simparica Trio Products — Growth Leaders & New Top 10 Entrants
Based on July 2026 data, this shortlist surfaces the two kinds of ASIN worth keeping an eye on — the ones that just broke into the Top 10, and the ones growing fastest month over month. On the growth side, B06XJS4HG7 leads positive momentum with ▲ 100.0% MoM growth on 2K units, with B07R9GX4XR close behind at ▲ 60.0% MoM on 8K units.
The two signals carry different weight. A fresh entrant means share has already changed hands — an incumbent gave up its place to make room, so any competitive set drawn up a month ago is now out of date. A steep growth rate works as the earlier warning: it marks demand that is still compounding, usually a month or two before the ranking catches up to it.

B06XJS4HG7
Advantus Dog Fast Acting Oral Flea Treatment Soft Chewable 23 - 110 lbs. | 30 ct.
Price
$70.68
Rating
4.2
Reviews
14.3K
Latest month sales

B07R9GX4XR
TevraPet Actispot II Flea Treatment for Large Cats 9+ lbs | 6 Doses | Powerful Prevention and Control
Price
$29.97
Rating
4.2
Reviews
10.5K
Latest month sales

B00I0BXQ6Q
K9 Advantix II Small Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 4-10 lbs. | 2-Mo Supply
Unlock to view ASIN details and product titles
Price
$35.62
Rating
4.3
Reviews
15.4K
Latest month sales
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