Best Selling Otc: See Top Product Rankings by Sales Volume & Market Trends

June 2026
136 Products Tracked

Looking for the most popular otc products in the market? Our report leverages real Amazon monthly sales data to identify the best-performing products and the fastest-growing opportunities within the search results for the keyword "otc." Whether you're searching for winning products to launch or monitoring market trends and competitor performance, this report provides the insights you need.

Based on monthly sales analytics, our Shoppers' Top Picks highlights that ASIN B09541P9WH currently leads the otc market with 100K monthly sales, followed closely by B00HQRCNWI with 70K monthly sales and B00008BRR8 with 40K monthly sales. By tracking competitor sales performance and shifts in market demand, sellers can uncover emerging opportunities and make more informed product and marketing decisions.

🏆Shoppers' Top PicksAmazon
by monthly sales June 2026
Amazon Basics Double-Tipped Cotton Swabs for Personal Hygiene and Baby Care, Cotton, Versatile, Baby Safe, 500 Count
1
B09541P9WH
$2.68·
4.7
Units/sold100K
Benadryl Topical Itch Relief Gel, Extra Strength, Contains 2% Diphenhydramine HCl, Soothing Relief from Scrapes, Insect Bites, Sunburn and More, Great for Outdoors, 3.5 fl oz
2
B00HQRCNWI
$6.48·
4.6
Units/sold70K
Refresh Tears Eye Drop Liquid Lubricant Bottle, 0.51 Ounce, 2 Pack
3
B00008BRR8
$13.07·
4.8
Units/sold40K

Top Selling Otc

As of June 2026, we analyzed 136 tracked products in Amazon's "otc" search results and generated the following sales chart and product rankings based on monthly sales data. The ranking below highlights the Top 10 products by estimated monthly sales. According to the latest data, these products generated between 10,000 and 100,000 monthly sales. B09541P9WH leads the otc market with an estimated 100,000 monthly sales, up 1.5% from the previous month.

136Products Tracked
39,000Top 10 Avg. Sales
$9.30Top 10 Avg. Price
4.7Top 10 Avg. Rating
🏆
Amazon Basics Double-Tipped Cotton Swabs for Personal Hygiene and Baby Care, Cotton, Versatile, Baby Safe, 500 Count
#1
B09541P9WH

Amazon Basics Double-Tipped Cotton Swabs for Personal Hygiene and Baby Care, Cotton, Versatile, Baby Safe, 500 Count

100,000
▲ 1.5%
Units Sold/mo
$2.68
Price
4.7
Rating
75.9K
Reviews
2
Benadryl Topical Itch Relief Gel, Extra Strength, Contains 2% Diphenhydramine HCl, Soothing Relief from Scrapes, Insect Bites, Sunburn and More, Great for Outdoors, 3.5 fl oz
B00HQRCNWI
$6.48
4.6 (44.2K)
Benadryl Topical Itch Relief Gel, Extra Strength, Contains 2% Diphenhydramine HCl, Soothing Relief from Scrapes, Insect Bites, Sunburn and More, Great for Outdoors, 3.5 fl oz
70,000 Units Sold/mo▼ 40.0%
3
Refresh Tears Eye Drop Liquid Lubricant Bottle, 0.51 Ounce, 2 Pack
B00008BRR8
$13.07
4.8 (34.3K)
Refresh Tears Eye Drop Liquid Lubricant Bottle, 0.51 Ounce, 2 Pack
40,000 Units Sold/mo▼ 85.0%
4
Cortizone-10 Maximum Strength Soothing Aloe Itch Relief Cream, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac & More, 2 oz
B0BJMQBSKJ
$7.97
4.7 (11.1K)
Cortizone-10 Maximum Strength Soothing Aloe Itch Relief Cream, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac & More, 2 oz
40,000 Units Sold/mo
5
Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each
B0036B8QL0
$14.98
4.8 (34.5K)
Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each
30,000 Units Sold/mo▼ 40.0%
10
Vashe Wound Solution OTC | Pure Hypochlorous Acid-Preserved Wound Cleanser | Home Wound Care | Non-Cytotoxic and Skin-Neutral pH | 8.5 Fl Oz
B019660RPG
$23.99
4.8 (8.4K)
Vashe Wound Solution OTC | Pure Hypochlorous Acid-Preserved Wound Cleanser | Home Wound Care | Non-Cytotoxic and Skin-Neutral pH | 8.5 Fl Oz
10,000 Units Sold/mo
View All 136 Products & Deep InsightsGet full access to sales data, trends, and market analysis

For sellers and category managers benchmarking the otc price landscape, we segmented all 136 tracked listings in Amazon's live "otc" search results across the full price spectrum, and surfaced the top 3 price tiers by share below to highlight where competition concentrates and where pricing gaps exist.

Leading the distribution, the $20.00 ~ $50.00 band is the category's best otc price zone, absorbing 23% of the assortment (93 products) — this is where listing density is highest and where new entrants face the steepest competition for share-of-voice. Use the tier breakdown below to identify the top-ranking ASIN, monthly sales velocity, and rating profile within each band — essential inputs for pricing strategy, sourcing decisions, and competitive benchmarking in the otc category.

Top 3 Price Tiers

$20.00 ~ $50.00 is the most competitive price tier, containing 23% of tracked products.

Sweet Spot
$20.00 ~ $50.00
Tier 1
23%
93 products

Top products in this price tier

#1
B09541P9WH
$2.68
100k Units Sold/mo
Unlock Top Performers
#2
$10.00 ~ $20.00
Tier 2
22%
86 products
$0.00 ~ $10.00
Tier 3
17%
67 products
$100.00 ~ $200.00
12%
Unlock to view all price tier distributions and their ASIN sales contributions

"Otc" Search Volume and Market Trends on Amazon

Amazon keyword search volume data for "otc" in the US marketplace. This report provides insights into keyword search volume, Amazon search trends, competition levels, and conversion efficiency for sellers and brands.

During the week of 2026-05-31 to 2026-06-06, the Amazon USweekly search volume for "otc" was approximately 465 searches. The keyword currently holds an Amazon Search Frequency Rank (SFR) of #394,554, climbing 82,392 positions from the previous week. Additionally, the top 3 products for this keyword capture 21.4% of the total click share and 26.9% of the conversion share, indicating the level of market concentration.

Amazon Search Term
Weekly

otc

ASINSIGHT
Search Frequency Rank
394,554
82,392
Search Volume
465
21.7%
Top 3 Click Share
21.4%
Top 3 Conv. Share
26.9%

Search Volume Trend

Past 3 Years
Past 4 Months
Recent 8 months
Weekly Search Volume
465
View full trends for the past 3 years
JunJulAugSepOctNovDecJanFebMarAprMay
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